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This means that only a fraction of the ingested glutathione may reach the bloodstream and exert its beneficial effects

To further explore the in vivo functions of Keap1 in adult MuSCs, we first generated a tamoxifen (TMX)-inducible MuSC-specific Keap1 knockout mouse strain (designated as Keap1 conditional knockout or Keap1 cKO thereafter) using the CreER/LoxP system